The missing link could be a hormone called ALDOSTERONE.
Aldosterone
(al-dah-stuh-rohn) and high blood pressure
If you are taking two or more blood pressure medicines and still have high blood pressure, could something be working against your best efforts? Aldosterone is a hormone made in the kidneys that helps regulate blood pressure. But in some people, aldosterone could be the reason for high blood pressure.
Today, there are no high blood pressure medicines available that directly target aldosterone.
But there’s good news: doctors are finding out about different ways to target aldosterone directly.
Are you ready to take action?See how aldosterone works
Tap the arrows below to learn more
These are your kidneys and adrenal glands
Renin
Aldosterone
Sodium
Water
High blood pressure is a warning sign
People taking two or more blood pressure medicines who still have high blood pressure are living with an increased risk of serious health problems like heart damage, stroke, kidney disease, and dementia.
People with high blood pressure have an even higher risk of heart attack and stroke in the morning.
This is due to several factors, including a natural morning spike in blood pressure and heart rate. Routinely monitor your blood pressure in the morning and at bedtime to understand your levels over 24 hours.
Not all blood pressure medicines work 24 hours a day.
Each additional 10-point drop in the top number of your blood pressure:
Learn more. Our downloadable brochure can help.
Download nowReduce your blood pressure to help reduce your risk
For most people with high blood pressure, clinically known as hypertension, the American Heart Association recommends maintaining blood pressure consistently lower than 130/80 mm Hg. Set a specific goal with your doctor. Reaching your goal reduces your risk and could mean more time spent enjoying the activities you love.
Tap the dial to explore the different blood pressure stages

Normal Blood Pressure
Systolic:
<120
Diastolic:
<80
- Systolic blood pressure is the first (top/upper) number. It measures the pressure your blood is pushing against your artery walls when the heart beats
- Diastolic blood pressure is the second (bottom/lower) number. It measures the pressure your blood is pushing against your artery walls while the heart muscle rests between beats
Be consistent about taking your blood pressure
Getting to your goal is more than having a few good blood pressure readings. Always log your blood pressure at least once in the morning and once at bedtime and share your readings with your doctor at your next appointment.
American Heart Association tips for measuring your blood pressure
Tap numbers to view tips
Avoid smoking, caffeine, or exercise for at least 30 minutes before measuring

